Flutivate cream or Fluticasone Propionate Cream is a topical corticosteroid. It has anti-inflammatory, antipruritic, and vasoconstrictive properties.
Name of Drug
Flutivate cream 20g (Fluticasone Propionate IP 0.005% w/w) It is sometimes also referred to as Cutivate cream or Fluticasone Propionate ointment.
Manufacturer of Flutivate Cream
Active Pharmaceutical Ingredient in Flutivate cream
The active pharmaceutical ingredient is Fluticasone Propionate IP 0.005% w/w.
Uses of Flutivate cream (Fluticasone Propionate Cream)
Flutivate cream is used for the treatment of eczema, psoriasis, allergies and rash.
Apply a thin film of medication (Fluticasone Propionate ointment) to the affected area and gently rub in, usually 1-2 times daily or as directed by your doctor.
Drug Class and Mechanism
This medication belongs to the class of topical corticosteroids.
Like other topical corticosteroids, Fluticasone propionate has anti-inflammatory, antipruritic, and vasoconstrictive properties. The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.